The Nucleotide Company.

Founded in 2003 in the vicinity of the German capital Berlin, Larova produces pivotal PCR reagents and is one of only a handful of original manufacturers of dexoxyribonucleotides (dNTPs) in the world.

What we do

dNTPs are the building blocks of the DNA created in PCR. Despite their vital role, they are often overlooked as a source of problems and impurities. At Larova, we understand that minor impurities in these nucleotides often inhibit the DNA polymerases and reduce the functional lifetime of the enzyme in the PCR. These impurities are often common by-products of the chemical synthesis of nucleotides. That’s why we use enzymes to produce our nucleotides, giving our dNTPs the best performance possible.

In addition to dNTPs, Larova offers a range of polymerases, reagents, and master mixes for PCR. These reagents take advantage of our high performance dNTPs to deliver reliable and reproducible high performance for your experiments.

The Team

Dr. Mathias Gruen
Dr. Mathias GruenManaging Director
Mathias studied Chemistry in Dortmund, London (UCL) and Adelaide.

He spent his graduate research at EMBL Heidelberg & Max-Planck-Institute for molecular Physiology, and continued research at post-doc positions at MPI and Harvard.

In 2002 he joined The Boston Consulting Group with a focus on biotech, health care, and financial projects. In 2003 he moved to Jena Bioscience group as CEO/CFO and as Larova’s Managing Director. Mathias is one of the founders of Jena Bioscience and Larova.
Dr. Larissa Consani Textor
Dr. Larissa Consani TextorHead of Business Development
Larissa studied Pharmacy and Biochemistry at the University of São Paulo (USP - Brazil), followed by a PhD at EMBL Hamburg for structural biology. Afterwards she worked as a Postdoc at the São Carlos Institute of Physics (IFSC - Brazil) and joined the research & development team at Jena Bioscience in 2012.

In 2014 Larissa became enrolled in the management of the daughter company Cellco Biotec and has been leading the business development team at Jena Bioscience & Larova since 2024.
Sibylle Bauer
Sibylle Bauer Legal Counsel
Sibylle is an attorney qualified in Germany and specialises in international business law.

She has a long-standing expertise in the pharmaceutical and biotech industry and joined the Jena Bioscience & Larova Group in 2003.
Dr. Andreas Licht
Dr. Andreas LichtHead of Production
Andreas studied Biochemistry/Molecular Biology at the University of Jena followed by a PhD and a Postdoctoral Position in the group of Bacterial Genetics. He joined Jena Bioscience in 2010 as a Research Scientist working on internal R&D projects and was promoted to Head of the Protein Expression group in 2012.

Andreas has been leading Larova's manufacturing team since 2021.
Frank Bieber
Frank BieberProduction Manager
Frank studied Technical Chemistry and Biotechnology in Mannheim. Thereafter he worked at EMBL Grenoble, followed by a diploma at EMBL Heidelberg.

Frank has been with Larova since 2003 and is responsible for nucleotide manufacturing with a chromatography unit capable of purifying nucleotides on a multi kilogram scale.
Dr. Silke Machata
Dr. Silke MachataHead of Quality Control
Silke studied Biology at the University of Würzburg, followed by a PhD in the Institute of Medical Microbiology at the University of Giessen. Afterwards she worked as a Postdoc at the Paris Cardiovascular Research Center in France followed by another Postdoc at the Microbial Immunology Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute in Jena.

Silke joined Larova in 2020 where she is responsible for Quality Control.
Christiane Kohls
Christiane KohlsQuality Management Officer
Christiane studied Biology with a focus on microbiology at the Friedrich-Schiller-University of Jena. She joined Jena Bioscience – Larova’s parent company – in 2002 as scientist in the LEXSY and Molecular biology department. Since 2014 Christiane is responsible for Quality Management and Quality Assurance.

ISO 9001 Certified Quality Management System

Larova has established a quality management system according to DIN EN ISO 9001, an environmental management system according to DIN EN ISO 14001.

We commit ourselves to work according to international standards and continuously improve our quality and environmental management system and our in house processes to meet our high quality standards.

Our structures and programs are designed to integrate environmental considerations throughout the company’s operations. We ensure the effective utilization of products needed for the manufacturing process and all other operations and preferably use materials that can be reused, recycled or disposed environmentally friendly. We also monitor the effective implementation of our environmental requirements and take measures accordingly. Larova goes beyond minimum legal compliance and continuously improves its environmental performance.

Larova Projects

Larova continually develops new products and technologies and is working on projects in a variety of areas.

For some of its projects, Larova receives funding from the Free State of Thuringia and the European Regional Development Fund (ERDF/EFRE). ERDF/EFRE invests in the following priorities: Research and development, support for small and medium-sized enterprises and the reduction of CO2 emissions in all sectors of the economy. The Joint Task for the Improvement of Regional Economic Structures (GRW) supports manufacturing companies or production-related service providers, craft businesses and tourism projects with investment grants.

Project GRW 53160021:
New company building for Larova.

Project 2023 FEE 0028:
New processes for the production of starting materials for the dNTP synthesis.