LAROVA - Newsletter

Issue August 2011

New in stock: Nucleoside-diphosphates (NDPs)

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Figure 1: Dynamic equilibrium of nucleoside diphosphate (NDP) and its triphosphate (NTP)

Nucleoside diphosphates (NDPs) are pivotal molecules in a plethora of cellular processes. The exothermic hydrolysis of ATP yielding ADP and inorganic phosphate (Pi) is the major source of biological energy, and ATP/ADP as well as GTP/GDP are involved in the signal transduction pathways by kinases and G-Proteins.

NDPs can be converted to their triphosphates (NTP) by kinase-mediated enzymatic attachment of one additional phosphate while NTPs in combination with a phosphatase are converted back to NDPs (Fig. 1).

NDPs are widely used in signal transduction research as cofactors and serve as templates for chemical or enzymatic synthesis of non-natural analogues.

LAROVA is now offering NDPs in powder form that

are of ≥ 96.0% purity (Reversed Phase HPLC) and can therefore, be directly used as cofactors or starting material for further modification

come at very affordable prices

Nucleoside-diphosphate (NDP) Lyophilisates

Cat. No.	Amount	Price (EUR)	Downloads
ADP NU-1198-1G	1 g	66,50
ADP NU-1198-5G	5 g	257,50
CDP NU-1199-100	100 mg	238,00
GDP NU-1172-100	100 mg	78,00
GDP NU-1172-1G	1 g	342,00
TDP NU-1207-10	10 mg	54,80
TDP NU-1207-100	100 mg	348,50
UDP NU-1206-100	100 mg	48,20
UDP NU-1206-500	500 mg	183,50

For more details and for ordering, please visit our website at

http://www.larova.com/index.php/en/1/catalog/314

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Rheinstr. 17B
14513 Teltow
Germany

Tel: +49 – 3328 – 3956 0
Fax: +49 – 3328 – 3956 39

E-Mail: info@larova.com

Register Court: Amtsgericht Potsdam, HRB 17 114 P
VAT No.: DE 231 513 961

Managing Director:
Dr. Mathias Grün

www.larova.com